Entrepreneurs and small business owners are their companies' strongest asset. That's why it's paramount they make health and well-being a top priority.

"What no entrepreneur can replace is themselves," says serial entrepreneur AJ Agrawal in a blog for Startupgrind.com.

See these tips on how to stay healthy while starting or running a small business.

Realize Impact on Business. It may not seem relevant at this moment, but your health and well-being can play a vital role in the success of your business now and in the future. That's definitely how entrepreneur Sean Kim sees it.

"In this fast-paced landscape, understanding the significance of well-being is paramount," writes Kim, CEO of language app companies Jumpspeak and Rype, in a post for Inc.

"As a startup founder who has dealt with his fair share of late nights and burnouts, I've learned the hard way how important health is to the success of my business."

Make the Time. A lack of time is often the main reason entrepreneurs and small business owners don't stay on top of their health. Yet, making the time is key to doing so.

"You have to set aside a certain amount of time during your day to stay healthy; otherwise, it's impossible to manage," writes Agrawal, founder of Verma Media, a San Francisco-based digital marketing agency.

How do you find the time? Work on prioritizing the types of activities and habits that create and sustain physical and mental health, such as exercise, nutritious meals, preventative health care, and stress management.

Take Work Breaks. Getting away from work is essential to your mental and physical health.

There's never going to be the perfect time to take a break from work because your schedule is impossible. However scheduling breaks provide the recharge your body and brain need to make better decisions and to fuel creativity and big picture thinking.

"The best entrepreneurs know when they need to take some time away from the business," says Agrawal in the Startupgrind post.   

Manage Stress.  While stress is just part of being an entrepreneur and small business owner,  understand the real value of managing it effectively.

In the Inc. article, Kim says successful entrepreneurs who embrace relaxation techniques, exercise, and mindfulness to help manage stress can attain clarity during turbulent times.

"This mental clarity empowers them to make strategic decisions, contributing to the growth and prosperity of their ventures."

Avoid Isolation. This is particularly pertinent advice for solopreneurs, but all small business owners and entrepreneurs should heed caution when it comes to social isolation, which is linked to a variety of mental and physical health risks.

Research indicates isolation and loneliness can increase risks for heart disease and stroke, type 2 diabetes, depression, and anxiety, according to the Centers for Disease Control and Prevention.

"Being an entrepreneur can be lonely — especially if you're operating a one-person show," writes entrepreneur and business consultant John Hall in a Fast Company article.

 "Solopreneurs may not have the stresses of managing a staff, but the isolation can produce a different type of anxiety," says Hall, co-founder of the scheduling app Calendar and author of the book "Top of Mind."

When you're starting or running a business, you're inevitably spending so much time working that there's little time left to connect with others, and social interactions can drop off the priority list.

But the isolation could eventually impact your mental health in not-so-good ways, says Hall. "I've learned that surrounding myself with people who support me does wonders for my state of mind."